Stem Cell Treatment for Autism
What is Autism?
Autism is a spectrum of disorders characterized by marked abnormalities in communication and social interactions. Two common consistent findings are associated in children with this disorder: 1) diminished oxygenation in specific areas of the brain and 2) a chronic immunologically mediated inflammatory condition in the gut.
what is the rationale behind using stem cells for treating autism?
Current investigational therapies for autism attempt to reverse these abnormalities through administration of antibiotics, anti-inflammatory agents, and hyperbaric oxygen. Unfortunately, none of these approaches address the root causes of oxygen deprivation and intestinal inflammation.
Mesenchymal stem cells can regulate the immune system. It is thought that they may help to reverse inflammatory conditions and is currently in the final stages of clinical trials in the US for Crohn’s disease, a condition resembling the gut inflammation in autistic children. The CD34 stem cells have been shown to induce generation of new blood vessels in tissue that lack oxygen. It is thought that these stem cells may help increase the blood flow in the temporal region of the brain, an area that is believed to be not adequately oxygenated in autistic children.
Through administration of mesenchymal and CD34 stem cells, we have observed improvement in patients treated at our facilities. The biological basis for our scientists in the peer published this treatment method reviewed “Journal of Translational Medicine”.
Where do the Stem Cells come from?
Typically the stem cells are recovered from donated umbilical cords. The two cell types are CD 34+ and mesenchymal cells. These cells are screened for viruses and bacteria to International Blood Bank Standards.
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